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F. Gaboriau, M. Cheron, C. Petit and J. Bolard, “Heat-In- duced Superaggregation of Amphotericin B Reduces Its in Vitro Toxicity: A New Way to Improve Its Therapeutic Index,” Antimicrobial Agents and Chemotherapy, Vol. 41, No. 11, 1997, pp. 2345-2351.

has been cited by the following article:

• TITLE: Study of Renal Toxicity in Wistar Rats Following the Action of Amphotericin B Solution Prepared under Extreme pH Conditions

  AUTHORS: Lamia Belkherroubi-Sari, Zahia Boucherit, Kebir Boucherit, Slimane Belbraouet

  KEYWORDS: Amphotericin B, Renal Toxicity, Candida albicans

  JOURNAL NAME: Food and Nutrition Sciences, Vol.2 No.7, September 20, 2011

  ABSTRACT: Our study related to the renal toxicity of Wistar rats induced by solutions of amphotericin B prepared under extreme conditions of pH (5.4 and 10.8). The results obtained show that with pH 5.4 of stock solution, urea and creatinin rate blood is not disturbed. These means that the renal function is not deteriorated by the amphotericin B. Furthers, treatment of animals infected by the yeast Candida albicans, with the solution of amphotericin B prepared at pH 5.4 and injected at 0.5 mg of AmB/Kg every 24 hours, seems to be effective.