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Inagaki, T., Miyaoka, T., Okazaki, S., Yasuda, H., Kawamukai, T., Utani, E., Wake, R., Hayashida, M., Horiguchi, J. and Tsuji, S. (2010) High Salivary Alpha-Amylase Levels in Patients with Schizophrenia: A Pilot Study. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 34, 688-691.

has been cited by the following article:

• TITLE: Increase in Salivary Alpha-Amylase Levels among Non-Attending Junior High School Students Diagnosed with Social Anxiety Disorder

  AUTHORS: Takuji Inagaki, Michiharu Nagahama, Kiminori Kawano, Rei Wake, Tsuyoshi Miyaoka, Jun Horiguchi

  KEYWORDS: Autonomic Function, Junior High School, Salivary Alpha-Amylase, School Non-Attendance, Social Anxiety Disorder

  JOURNAL NAME: Journal of Behavioral and Brain Science, Vol.7 No.8, August 18, 2017

  ABSTRACT: Purpose: Several studies have demonstrated that the measurement of salivary alpha-amylase (sAA) levels is a useful tool for evaluating the autonomic nervous system. Psychosocial stress increases the release of sAA as a useful marker for autonomic nervous system (ANS). To our knowledge, although some studies have evaluated sAA levels under psychosocial stress, no studies have investigated the changes in sAA activity that occur in junior high school students who are not attending school due to social anxiety disorder (SAD). We aimed to investigate the relationship between the sAA levels and psychiatric states of such patients. Methods: The study subjects consisted of SAD patients (n = 39) and healthy controls (n = 57). We used a portable hand-held monitor to measure the level of sAA and State-Trait Anxiety Index (STAI) to evaluate the psychiatric state. Results: The patients’ sAA activity was significantly higher than that of the controls (n = 57) (p p p p