TITLE:
Two Cases of Hallopeau Type of Pemphigus Vegetans in Two Women in Burkina Faso
AUTHORS:
Jean-Baptiste Andonaba, Issouf Konaté, Konségré Valentin, Boukary Diallo, Muriel S Ouédraogo, Nina Néssiné Korsaga-Somé
KEYWORDS:
Pemphigus Vegetans, Hallopeau, Black Women, Burkina Faso
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.7 No.3,
August
7,
2017
ABSTRACT: Pemphigus of Hallopeau (PH) is a mild and pustular form of pemphigus vegetans,
termed initially as “pyodermite végétante” described by Hallopeau. We
report cases in two black women. Two women aged 32 and 36 respectively
(case 1 and case 2) were seen for a pustulosis associated with blisters and erosions.
Their history and their review have found the mouth ulcerations. The
clinical examination showed pustules on the cephalic end, the trunk, the limbs
and the large folds. Lesions had a polycyclic aspect and spread in a centrifugal
way, developing towards budding, squamous and scabby erosions quickly
surrounded by new pustules. Regression left a pigmented macula. Histological
examination of the skin lesion showed images similar to vulgaris pemphigus
(PV), together with hyperacanthosis and papillomatosis. Aspects observed in
immunofluorescence were identical to those of PV (case1). General corticoid
therapy led to a rapid disappearance of lesions in Case 1 but in Case 2 the
Lever protocol combining corticoid and methotrexate have been used. PH is
rarely described in our regions. Clinical diagnosis is not obvious for the uninitiated.
Beyond the clinical presentation, PH has the same paraclinical diagnosis
and the same treatment as PV.