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Badger, A.M., Schwartz, D.A., Picker, D.H., Dorman, J.W., Bradley, F.C., Cheeseman, E.N., Dimartino, M.J., Hanna, N. and Mirabelli, C.K. (1991) Cheminform Abstract: Antiarthritic and Suppressor Cell Inducing Activity of Azaspiranes: Structure-Function Relationships of a Novel Class of Immunomodulatory Agents. Journal of Medicinal Chemistry, 22, 2963-2970.

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• TITLE: Advances in Effect of Germanium or Germanium Compounds on Animals—A Review

  AUTHORS: Lingjun Li, Tao Ruan, Yingnan Lyu, Bangyuan Wu

  KEYWORDS: Germanium, Germanium Compounds, Physiological Function, Toxicity, Immunity

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.5 No.7, July 25, 2017

  ABSTRACT: An increasing number of researches have been focused on the relationship between trace elements and animal health. Germanium, as a widely used trace element, exists ubiquitously as germanium or germanium compounds in the living environment of human and animals, and plays important roles in animal production or health. With the intensive study of the physiological function of germanium and its compounds, the effects of germanium on animal physiological functions and health have been gradually confirmed. In this review, we discuss the metabolic distribution, physiological characteristics, biological functions, germanium deficiency and germanium toxicity. Furthermore, we focus on the effects of germanium or germanium compounds on the immunity of animals. It is concluded that germanium or germanium compounds not only has positive effect but also has negative effect on animals. This review aims to provide a reference for the future research or application of the germanium or germanium compounds on animals or human beings.