TITLE:
Clinical Case: About a Probable Case of Post-Transfusion Purpura in a Homozygous Sickle Cell
AUTHORS:
Rakotoniaina Andriamiarimbol Irène, Fenomama Jocia, Fenomanana Maminirina Sonia, Buscotin Eugenie, Rasamindrakotroka Andry, Rakoto Alson Olivat Aimé
KEYWORDS:
Post Transfusion Purpura, Thrombocytopenia, Sickle Cell Disease, Bumps
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.6 No.6,
June
30,
2017
ABSTRACT: Alloimmunization to platelet antigens exposes to a serious immunological incident. We report a probable case of a post-transfusion purpura from homozygous sickle cell child alloimmunized against platelet antigen. We detail the challenges of alloantibody identification and transfusion management. These challenges are due to the lack of laboratory techniques for typing HLA and HPA system and the use of leukocyte-depleted (filtered) blood products.