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Nho, J.-S., Lee, S.-Y., Kang, J.-M., Kim, M.-C., Choi, Y.-K., Shin, O.-Y., Kim, D.-S. and Kwon, M.-I. (2009) Effects of Maintaining a Remifentanil Infusion on the Recovery Profiles during Emergence from Anesthesia and Tracheal Extubation. British Journal of Anaesthesia, 103, 817-821.
https://doi.org/10.1093/bja/aep307

has been cited by the following article:

• TITLE: Comparison between the Effects of Alfentanil, Lidocaine and Their Composition in Controlling the Hemodynamic Responses at the Time of Awake Extubation of Patients

  AUTHORS: Ali Alizadeh, Mahmoud Aghaziarati, Nasim Zarin

  KEYWORDS: Alfentanil, Lidocaine, Hemodynamic Responses

  JOURNAL NAME: International Journal of Clinical Medicine, Vol.8 No.6, June 28, 2017

  ABSTRACT: Background and aim: Instability in the hemodynamic symptoms has been common at the time of extubation in patients and the cause to create the side effects. The aim of this research was to study the effect of injection of Alfentanil, Lidocaine and their composition in reduction of side effects arising from extubation. Materials and methods: 172 patients (20 - 40 years old) that referred to Shahid Rajaee Hospital in 2014 and had been under the orthopedic surgery, were divided randomly and by using colored cards into four equal groups (43 patients in each group). Alfentanil (5 microgram/kilogram) was injected to the first group. The second group received Lidocaine (1 milligram/ kilogram). The composition of these two drugs was injected to the third group and the normal equal volume of Saline was injected to the fourth group which was the control group. The means of systolic and diastolic blood pressure, average arterial pressure and the number of heartbeat at the time of extubation were measured and registered 1, 5, 10, 15 and 20 minutes after extubation. Also, the amount of situation of bucking after extubation was registered in the groups. Results: The demographic results were similar in all groups. The mean of systolic blood pressure and number of heartbeats in the group of Alfentanil and composition of Alfentanil-Lidocaine had significant reduction (p 0.05). The situation of bucking in three treatment groups had significant reduction in comparison with control group. Conclusion: Alfentanil and composition of it with Lidocaine both had caused reducing the systolic blood pressure and heartbeats.