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Aarabi, S., Bhatt, K.A., Shi, Y., Paterno, J., Chang, E.I., Loh, S.A., Holmes, J.W., Longaker, M.T., Yee, H. and Gurtner, G.C. (2007) Mechanical Load Initiates Hypertrophic Scar Formation through Decreased Cellular Apoptosis. The FASEB Journal, 21, 3250-3261.
https://doi.org/10.1096/fj.07-8218com

has been cited by the following article:

• TITLE: The Use of Zigs and Zags to Reduce Scarring over “Keloid Triangles” during Excisional Surgery: Biomechanics, Review and Recommendations

  AUTHORS: Sharad P. Paul

  KEYWORDS: Keloid, Hypertrophic Scar, Scarring, Wound, Excision, Ellipse, Chest, Sternum

  JOURNAL NAME: Surgical Science, Vol.8 No.6, June 19, 2017

  ABSTRACT: Aim: The sternal region, cervico-mandibular region and the intra-mammary region have been the bane of many cutaneous surgeons, with a higher propensity for poor scarring and wound complications. In this article, the author undertakes a review of different methods of breaking up scars by utilizing zigs and zags, and conducts a pigskin study to measure the reduction in tension that can be achieved by using a simple zigzag technique while performing excisions. Methods: A pigskin study conducted into the use of the simple zigzag to reduce the tension (and thereby scarring) of surgical wounds is reported here, and comparison and review is undertaken of the biomechanics of elliptical excisions and traditional Z-plasties. Results: Using a simple zigzag reduces tension across the midpoint of the scar more effectively than a Z-plasty or a simple elliptical excision. Conclusion: The techniques of breaking up a scar or incision line by using zigs and zags, in a means to reduce scarring, are not new. However, each of these techniques has specific advantages and disadvantages that need consideration by the surgeon. In this paper, a pigskin study is conducted into the use of the simple zigzag to reduce the tension (and thereby reduce the risk of poor scarring) of surgical wounds.