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Majoumo-Mbe, F., Nde, D.T., Mukoko, I.N., Offiong, E.O. and Nfor, E.N. (2016) Synthesis, Crystal and Molecular Structure of Manganese (II) Complex of 2-Acetylpyridine N(4) Ethylthiosemicarbazone. Communications in Inorganic Synthesis, 4, 5-11.

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• TITLE: Synthesis, Molecular Structure and Antibacterial Activity of Benzylmethyl-4-Methyl-3-Thiosemicarbazone

  AUTHORS: James A. Mbah, Godfred A. Ayimele, Elvis N. Eyonganyoh, Emmanuel N. Nfor

  KEYWORDS: Benzylmethyl-4-Methyl-3-Thiosemicarbazone, Antibacterial Activity, Crystal Structure

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.7 No.2, May 24, 2017

  ABSTRACT: A novel Schiff base, benzylmethyl-4-methyl-3-thiosemicarbazone (BMM) de-rived from benzylmethylketone and 4-methylthiosemicarbazide was synthe-sized and characterized by elemental analysis, spectroscopic methods (IR, 1H NMR, 13C NMR) and physical means. The single crystal structure analysis of the Schiff base reveals that it crystallizes in a monoclinic system in the P21/c space group. BMM revealed moderate antibacterial activity on three bacterial strains with diameter zone of inhibition of 16 mm (E. coli), 14 mm (K. pneumonia) and 13 mm (S. epider-midis) compared with the standard drug, ciprofloxacin.