TITLE:
Catalyst Free One-Pot Synthesis of Chromeno Quinolines and Their Antibacterial Activity
AUTHORS:
Sruthi Vasamsetty, Sunitha Medidi, Satheesh Ampolu, Ravi Kumar Majji, Mastan Rao Kotupalli, Chikurumilli China Satyanarayana, Annapurna Nowduri, Paul Douglas Sanasi
KEYWORDS:
Dimethyl-Dihydro-7H-Chromeno[3, 2-h]Quinolin-8(9H)-One Derivatives Syn-thesis, Biological Activity and One-Pot Condensation
JOURNAL NAME:
Green and Sustainable Chemistry,
Vol.7 No.2,
May
22,
2017
ABSTRACT: An efficient greener one pot synthesis of dimethyl-dihydro-7H-chromeno[3, 2-h]quinolin-8(9H)-one derivatives has been synthesized through cyclization of aromatic aldehyde, dimidone and 8-hydroxy-quinoline through one-pot condensation method is described. The synthesized compounds are screened for further biological activities against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis, Bacillus using cut plate method and disc diffusion method.