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Astrup, A., Toubro, S., Cannon, S., Hein, P. and Madsen, J. (1991) Thermogenic Synergism between Ephedrine and Caffeine in Healthy Volunteers: A Double-Blind, Placebo-Controlled Study. Metabolism, 40, 323-329. https://doi.org/10.1016/0026-0495(91)90117-F

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• TITLE: Testing Low Doses of Caffeine on Respiratory Resistance Using the Airflow Perturbation Device

  AUTHORS: Mary Kate Montgomery, Allen Luk, Arthur T. Johnson, Jafar Vossoughi

  KEYWORDS: Respiratory Resistance, Caffeine

  JOURNAL NAME: Open Journal of Respiratory Diseases, Vol.7 No.2, May 9, 2017

  ABSTRACT: Research reports on pulmonary function measurements often mention caffeine abstinence as a condition for testing subjects. Yet, the effects of caffeine on respiration are not well documented. This study was intended to investigate the physiological effects of caffeine on respiratory resistance measurements and the necessity of caffeine avoidance in such testing. Thirty-one subjects were administered caffeine in pill form for dosages in the range of 3 - 4.5 mg/kg body weight. Respiratory resistance was measured with the Airflow Perturbation Device every 15 minutes after caffeine ingestion until a full hour of elapsed time. No changes were noted in inhalation, exhalation, and average respiratory resistances during the times of measurements. The conclusion is that for low dosages of caffeine, respiratory resistance measurements are not affected by caffeine ingestion prior to testing.