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Liberty, G., Gal, M., Halevey-Shalem, T., Michaelson-Cohen, R., Galoyan, N., Hyman, J., et al. (2007) Lidocaine-Prilocaine (EMLA) Cream as Analgesia for Hysterosalpingography: A Prospective, Randomized, Controlled, Double Blinded Study. Human Reproduction, 22, 1335-1339.
https://doi.org/10.1093/humrep/del517

has been cited by the following article:

• TITLE: Comparing EMLA Cream and Ibuprofen on Pain after Insertion of Copper Intrauterine Device

  AUTHORS: Tahereh Boryri, Farnoosh Khojasteh

  KEYWORDS: EMLA Cream, Ibuprofen, Women-Pain Severity, IUD

  JOURNAL NAME: International Journal of Clinical Medicine, Vol.8 No.3, March 31, 2017

  ABSTRACT: Background and Objective: IUD is a safe, effective, and reversible method throughout the world, particularly in areas where population growth is too much. One of the main barriers to use IUD is the fear and pain of its insertion. Therefore, it is necessary to take measures to reduce the pain, and this study was conducted to investigate the effect of EMLA cream and ibuprofen on pain during IUD insertion. Materials and Methods: This randomized controlled clinical trial study was conducted on 120 women who admitted to Imam Javad health center in Zahedan in 2015-2016 for insertion of IUD. Women who admitted to this center were randomly assigned into 3 groups of EMLA group (n = 40), ibuprofen (n = 40), and control or placebo (n = 40). These women have no problem to insert IUD. Demographic data and pain level were recorded in a questionnaire based on Johnson’s Visual analog scale of pain at 3 stages of IUD insertion, and all IUDs were inserted by a midwife and then data were analyzed by SPSS software. Findings: The results of this research show that the lowest level of pain severity at three stages of insertion related to the EMLA cream (P Conclusion: The results of the study showed that, compared to ibuprofen and placebo, EMLA cream is a safe method in reducing pain caused by IUD insertion in all stages of IUD insertion.