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Saxon, L.A., Bristow, M.R., Boehmer, J., Krueger, S., Kass, D.A., De Marco, T., Carson, P., DiCarlo, L., Feldman, A.M., Galle, E. and Ecklund, F. (2006) Predictors of Sudden Cardiac Death and Appropriate Shock in the Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) Trial. Circulation, 114, 2766-2772.
https://doi.org/10.1161/CIRCULATIONAHA.106.642892

has been cited by the following article:

• TITLE: Clinical Predictors of Appropriate Implantable Cardioverter-Defibrillator Therapies in Primary Prevention: A Retrospective Study

  AUTHORS: Chiara Devecchi, Eraldo Occhetta, Vincenzo Alessandro Galiffa, Gabriele Dell’Era, Andrea Magnani, Francesco Rametta, Paolo Nicola Marino

  KEYWORDS: ICD, Primary Prevention, Predictors, Appropriate Therapy, Complications

  JOURNAL NAME: World Journal of Cardiovascular Diseases, Vol.7 No.3, March 30, 2017

  ABSTRACT: Implantable cardioverter-defibrillator (ICD) in heart failure with reduced ejection fraction (EF) patients reduces risk for sudden cardiac death (SCD). Previous data suggest that the benefit of ICD therapy in real life may be lower than expected from the results of controlled studies and only about one-third of ICD patients receive appropriate therapies. Nevertheless, all ICD patients are at risk of perioperative complications and inappropriate shocks. We retrospectively studied 613 patients undergoing ICD for primary prevention in 2002-2015; we excluded inherited arrhythmogenic syndromes. Patients underwent 12-leads ECG, echocardiography, laboratory tests and quality of life questionnaire. We evaluated comorbidities, appropriate therapies, complications and all-cause mortality. Consecutive patients (age 67 ± 10 years, 81% males, 59% ischaemic aetiology) were followed for 51 ± 31 months. 198 patients (32%) received appropriate ICD therapy, 93 (15%) had inappropriate shocks, 53 (8%) had at least one complication (electrode dysfunction, infection and pocket related) and 191 (33%) died. Multivariate analysis showed atrial fibrillation (OR = 1.8, CI = 1.27 - 2.53; p