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Nunn, J. and Hill, D. (1960) Respiratory Dead Space and Arterial to End Tidal CO2 Tension Difference in Anesthetized Man. Journal of Applied Physiology, 15, 383-389.

has been cited by the following article:

• TITLE: Unexpected Increase in Arterial to End-Tidal CO2 Gradient in a Child Undergoing Embolization of MAPCAs

  AUTHORS: Saifeldin A. Mahmoud, Khaled A. Sedeek, Patrick M. McQuillan

  KEYWORDS: Multiple Aorto-Pulmonary Collateral Arteries (MAPCAs), Pa-etCO2 Gradient, Ventilation-Perfusion (V/Q) Relationship

  JOURNAL NAME: Open Journal of Anesthesiology, Vol.7 No.3, March 29, 2017

  ABSTRACT: A 17-month-old infant with multiple aorto-pulmonary collateral arteries (MAPCAs) and pulmonary hypertension presented for diagnostic catheterization. On the day of the procedure, the infant was asymptomatic with oxygen saturation in the 90’s on 1.0 L/min O2 nasal cannula. His parents denied any recent illness. During the procedure, one coil was inadvertently embolized into the right lung resulting in markedly increased pulmonary artery pressures. The Pa-etCO2 gradient increased to 25 mmHg from a baseline of 2 mmHg. Therapy was initiated to reduce the PaCO2. The patient could not be weaned from mechanical ventilation due to elevated PA pressures.