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Violante, I.R., Ribeiro, M.J., Edden, R.A., Guimaraes, P., Bernardino, I., Rebola, J., Cunha, G., Silva, E. and Castelo-Branco, M. (2013) GABA Deficit in the Visual Cortex of Patients with Neurofibromatosis Type 1: Genotype-Phenotype Correlations and Functional Impact. Brain, 136, 918-925.
https://doi.org/10.1093/brain/aws368
has been cited by the following article:
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TITLE:
Voxel Placement Precision for GABA-Edited Magnetic Resonance Spectroscopy
AUTHORS:
Xue Bai, Ashley D. Harris, Tao Gong, Nicolaas A. J. Puts, Guangbin Wang, Michael Schär, Peter B. Barker, Richard A. E. Edden
KEYWORDS:
MRS, Voxel Placement, Precision, Voxel Prescription, Registration
JOURNAL NAME:
Open Journal of Radiology,
Vol.7 No.1,
March
24,
2017
ABSTRACT: The purpose of the present study was to assess the reproducibility of voxel placement for GABA-edited MRS. GABA-edited MRS data were acquired in 13 healthy volunteers from (3 cm)3 voxel; and within the same session a second acquisition was independently prescribed. A three-dimensional voxel mask image was reconstructed in T1-image-space using the SVMask tool (in house software). Reproducibility of voxel placement was assessed using the Dice overlap coefficient, both within-subject and between-subject following co-registration of T1 images and transformation of voxel mask images to standard space. Within-subject overlap coefficients were 86% ± 5%. Between-subject overlap coefficients were 75% ± 10%. For the two voxel locations considered (occipital and sensorimotor), voxel overlap was very similar. Between-subject values are higher due to between-session effects, anatomical variability and volume mismatch in standard space. While surprisingly low in terms of volume overlap, the overlap coefficients correspond to acceptable linear displacements.