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Singh, S., Kumar, A., Patel, A., Tripathi, A., Kumar, D., and Verma, D. (2010) Silico 3D structure prediction and comparison of nucleocapsid protein of H1N1. Journal of Modelling and Simulation of Systems, 1, 108-111.

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• TITLE: Indonesian avian influenza H274Y mutant neuraminidase homology models assessment

  AUTHORS: Sigit Jaya Herlambang, Rosari Saleh

  KEYWORDS: Neuraminidase; Model Assessment; Homology Model; Mutant; Avian Influenza

  JOURNAL NAME: Journal of Biophysical Chemistry, Vol.2 No.3, August 11, 2011

  ABSTRACT: Five models of Indonesian H274Y mutant neuralminidase type 1 (N1) were generated from the template 3CKZ by homology modeling. The template has the best similarity percentage 97% with the model sequence. The models was evaluated to search the best model with DOPE, 3D-profiles and PROCHECK in a good rank. The results show model 3 as a potential model to be used in the simulation with the lowest DOPE score, highest verify-3D score and from Ramachandran plots we inferred that it also shared the 1st rank with model 4 based on the 99.4% of the residues found, without Glycine and Proline, at the most favoured and additionally allowed region of both model structures.