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Knobbe, C.B., Kieslich, A.T. and Reifenberger, G. (2005) Genetic Alteration and Expression of the Phosphoinositol-3-Kinase/AKT Pathway Gene PIK3CA and PIKE in Human Gliobblastomas. Neuropathol Appl Neurpbiol, 31, 486-490. https://doi.org/10.1111/j.1365-2990.2005.00660.x

has been cited by the following article:

• TITLE: The Expression of PI3K, AKT, β-Catenin and VEGFR2 in Medulloblastoma

  AUTHORS: Xiao Lin, Yu Li

  KEYWORDS: PI3K, AKT, β-Catenin, VEGFR2, Medulloblastoma

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.5 No.3, March 10, 2017

  ABSTRACT: Medulloblastoma (MB) is common tumor of the central nervous system in children. It’s reported that PI3K/AKT and Wnt signal pathway have important roles in MB. This study aims to investigate the expression of PI3K, AKT, Β-catenin and VEGFR-2 in MB to find a new pathway for MB. A total of 33 MB and 17 control brain cases were retrospectively evaluate d for PI3K, AKT, β-catenin and VEGFR-2 expression by immunohistochemical staining, and the relationship with clinical feature were analyzed. The positive rate of PI3K, AKT, β-catenin and VEGFR-2 in 33 MB were significantly greater than those in control group (P