TITLE:
Expression and Significance of IL-6 and bFGF in Human Tongue Squamous Cell Carcinoma
AUTHORS:
Ju-Hua Hou, Zheng-Bing He, Xiao-Ju Hou, Yuan-Yue Liu, Wen-Jiang Zhang, Juan Duan
KEYWORDS:
Tongue Squamous Cell Carcinoma, Il-6, bFGF, Tissue Array
JOURNAL NAME:
Journal of Cancer Therapy,
Vol.8 No.2,
February
22,
2017
ABSTRACT: Objective: To detect the expression and pathological significances of Interleukin-6 (IL-6) and basic fibroblast growth factor (bFGF) in tongue squamous cell carcinoma (TSCC). Methods: A tissue array was analyzed immunohistochemically. The expression levels of IL-6 and bFGF in tissues were recorded semi-quantitatively. Results: The positive expression of IL-6 in normal, benign tumor, and carcinoma groups was 12.50% ± 5.575%, 39.00% ± 1.41%, 77.26% ± 17.07% respectively, and the expression among the three groups showed significant differences (P P P Conclusion: It indicates that combining immunohistochemical examination of IL-6 and bFGF has an important reference value on the pathological diagnosis of tongue squamous cell carcinoma.