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Mansini, A.P., Rubio, P.L., Rossi, J.G., Gallego, M.S., Medina, A., Zubizarreta, P.A., Felice, M.S. and Alonso, C.N. (2013) Mutation Characterization in the GATA-1 Gene in Patients with Down’s Syndrome Diagnosed with Transient Abnormal Myelopoiesis or Acute Megakaryoblastic Leukemia. Archivos Argentinos de Pediatria, 111, 532-536.

has been cited by the following article:

• TITLE: Efficacy of Inchinkoto for Liver Cirrhosis in an Infant with Down Syndrome Complicated by Transient Myeloproliferative Disorder

  AUTHORS: Ryuta Washio, Masaya Takahashi, Sohsaku Yamanouchi, Masato Hirabayashi, Kenji Mine, Yukihiro Noda, Eriko Kanda, Atsushi Ohashi, Hirohide Kawasaki, Kazunari Kaneko

  KEYWORDS: Inchinkoto, Transient Myeloproliferative Disorder, Down Syndrome, Liver Fibrosis, Japanese Herbal Medicine

  JOURNAL NAME: Open Journal of Pediatrics, Vol.7 No.1, February 20, 2017

  ABSTRACT: Several patients with Down syndrome complicated by transient myeloproliferative disorder may develop liver cirrhosis for which no effective therapeutic agent exists. We report the infant with Down syndrome complicated by transient myeloproliferative disorder and liver cirrhosis who was successfully treated by Inchinkoto, the Japanese herbal medicine. In the present case, Inchinkoto appeared to prevent both histological and serological aggravation of liver cirrhosis. To the best of our knowledge, this is the first report of preventive effect of Inchinkoto on liver cirrhosis, and it can be a choice of treatment for infants with Down syndrome complicated by liver cirrhosis.