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[4] Mbinze, J.K., Nsangu, J.M., Maghe, E., Kobo, S., Mwanda, R., Mulumba, G., Bolavie, J.B., Bayebila, T.M., Borive, M.A., Hubert, Ph. and Marini, R.D. (2015) Application of Total Error Strategy in Validation of Affordable and Accessible UV-Visible Spectrophotometric Methods for Quality Control of Poor Medicines. American Journal of Analytical Chemistry, 6, 106-107.
https://doi.org/10.4236/ajac.2015.62010

has been cited by the following article:

• TITLE: UV Visible Spectrophotometric Determination of the Quality of Antiretroviral Drugs Distributed in Kinshasa

  AUTHORS: Erick Ntambwe Kamangu, Jérémie K. Mbinze, Arnold M. Mingu, Jacquie B. Bolavie, Georges Lelo Mvumbi, Richard Lunganza Kalala, Gauthier Kahunu Mesia, Mariano Lusakibanza, Jean Mavar, Roland D. Marini

  KEYWORDS: Spectrophotometry, UV-Visible, ARV, Kinshasa

  JOURNAL NAME: Open Access Library Journal, Vol.4 No.2, February 15, 2017

  ABSTRACT: Background: Antiretrovirals (ARVs) are the molecules used in the fight against infection by the Human Immunodeficiency Virus (HIV). Their main objective is to stop the virus from replicating and thus allow the immune system to recover. In 2001, the program to fight against HIV/AIDS United Nations (UNAIDS) and its partners has decided to strengthen the pharmaceutical channel and improve access to good quality care. Thus ARV quality control is recommended. Objective: The objective of this work was to monitor the quality of ARVs distributed in Kinshasa. Methodology: In this work, UV-visible spectrophotometry is used for the analysis of ARVs presented in simple form distributed in the city of Kinshasa. Results: The results of this work show that the stated and analyzed ARVs contain active ingredients; there is no placebo. Ten percent of these ARVs are non-compliant with regard to dosing of the active test. Conclusion: These results confirm the need to control these drugs to protect patients from adverse consequences related to their poor quality.