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Bayer Health Care Clinical Study Report (2000) Open, Randomized Three-Factorial (Treatment-Period-Sequence), Three-Treatment, Three-Period Latin Square Clinical Study for Comparison of a Fixed Combination of 500 mg Acetylsalicylic Acid/30 mg Pseudoephedrine versus Each of the Singe Active Ingredients (Pharmacokinetic Interaction Study) in 12 Healthy Male Volunteers. Report No. PH-29594.

has been cited by the following article:

• TITLE: Aspirin plus Pseudoephedrine (Aspirin Complex) for the Treatment of Symptoms of Upper Respiratory Tract Infection

  AUTHORS: Michael Voelker, Ronald Eccles, Uwe Gessner

  KEYWORDS: Aspirin, Acetylsalicylic Acid, Pseudoephedrine, Dissolution, Pharmacokinetic, Upper Respiratory Tract Infection, Clinical Studies

  JOURNAL NAME: Open Journal of Respiratory Diseases, Vol.7 No.1, February 7, 2017

  ABSTRACT: Upper respiratory tract infections or common colds are a multi-symptom disease which is usually symptomatically treated with fixed dose multi-active ingredient medicinal products which are commonly used as non-prescription and over the counter. However, the active ingredients combined require a particular and clinically sound justification. Analgesics and decongestant can be combined to treat simultaneously the prominent symptoms cold-related pain (e.g. headache, muscle aches and pains), fever, inflammationand nasal/sinus congestion. This overview provides a summary of the evidence supporting the combination of acetylsalicylic acid (aspirin) and pseudoephedrine available in the common cold product Aspirin® Complex.