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Nakajima, A., Aoki, Y., Shibata, Y., Sonobe, M., Terajima, F., Takahashi, H., Saito, M., Taniguchi, S., Yamada, M. and Nakagawa, K. (2014) Identification of Clinical Parameters Associated with Serum Oxidative Stress in Patients with Rheumatoid Arthritis. Modern Rheumatology, 24, 926-930.
https://doi.org/10.3109/14397595.2014.891495
has been cited by the following article:
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TITLE:
Tocilizumab Significantly Decreases Reactive Oxygen Species Level in Patients with Rheumatoid Arthritis
AUTHORS:
Naoki Kondo, Katsumitsu Arai, Takahiro Netsu, Tomotake Kanai, Hiroshige Sano, Go Okumura, Yasufumi Kijima, Junichi Fujisawa, Naoto Endo
KEYWORDS:
Tocilizumab, Rheumatoid Arthritis, Reactive Oxygen Species, Disease Activity Score 28
JOURNAL NAME:
Open Journal of Rheumatology and Autoimmune Diseases,
Vol.7 No.1,
January
11,
2017
ABSTRACT: To determine the effect of tocilizumab (TCZ) on reactive oxygen species (ROS) in 11 patients with rheumatoid arthritis (RA), reactive oxygen metabolites (d-ROM) were measured using a Free Radical Elective Evaluator. The Disease Activity Score (DAS28) and matrix metalloproteinase-3 (MMP-3) level were also evaluated. d-ROM measured 392 ± 110 Carratelli units [U. CARR] on initiation of TCZ, and significantly decreased to 237 ± 82, 248 ± 88, and 226 ± 91 U.CARR after 3, 6, and 12 months, respectively (p