TITLE:
A Case of Multiple Myeloma and Renal Failure in a Young Patient
AUTHORS:
Muftah Othman, Eiman Homid, Mohamed Sadek, Ali Rahil, Awad Rashed
KEYWORDS:
Myeloma Cast Nephropathy, Plasmapheresis, and High Cut-Off Hemodialysis
JOURNAL NAME:
Open Journal of Nephrology,
Vol.6 No.4,
December
16,
2016
ABSTRACT: Multiple myeloma is a malignant plasma cell disorder that affects the
kidney with various clinical
presentations. The most common renal manifestation of multiple myeloma
is myeloma cast nephropathy. We are describing a young patient with multiple myeloma presented with back pain, anemia and
renal impairment. The renal biopsy showed a myeloma cast nephropathy. She was treated with
myeloma chemotherapy, high cut-off
hemodialysis and autologous hematopoietic stem cell transplantation with good outcome. We report this rare
case of multiple myeloma presented
with myeloma cast nephropathy (MCN) in a young patient to describe the evidence of light chain removal strategies including plasmapheresis and high
cut-off hemodialysis for the management of myeloma cast nephropathy.