TITLE:
Peptic Ulcer Disease in CHUYO
AUTHORS:
A. Coulibaly, A. K. Sermé, H. Godonou, K. S. Somda, K. Cissé, Sia Romond, Kafando Roch, R. A. Sombié, A. Bougouma
KEYWORDS:
Peptic Ulcer Disease, Helicobacter pylori, Bleeding Perforation
JOURNAL NAME:
Open Journal of Gastroenterology,
Vol.6 No.11,
November
29,
2016
ABSTRACT: Background: Prevalence of Peptic Ulcer Disease (PUD)
is decreasing in developed countries since the use of the treatments for
eradication of Helicobacter pylori. Objectives:
To revalue the sociodemographic, clinical and evolutionary aspects of the PUD
among hospitalized patients in CHUYO. Methodology: This prospective study is related
to 65 files of patients hospitalized in hepato-gastroenterology and general
surgical services of the CHUYO between March 1st and August 31st, 2015. Results:
Hospital utilization rate was 6.59%. The average age of patients was 40.6 years
with extremes of 17 and 80 years. The sex ratio was 9.8. The location of the
ulcer was 69.23% in stomach. A notion of taking aggressive gastrointestinal
products was found in 62 patients (95.4%). The clinical picture was represented
by diffuse abdominal pain (76.92%), peritoneal irritation syndrome (64.61%) and
epigastric pain (56.92%), anemia (23.07%).
Gastric perforations (64.61%) and gastrointestinal bleeding (12.30%) were the main complications. Consumption of non-steroidal anti-inflammatory
drugs (NSAIDs) was found in 81.5% of cases. The management was medical and/or
surgical with an overall mortality rate of 7.7%. Conclusion: The PUD rate decreased
from 10.12% to 6.59% in 5 years. The complications are dominated by stomach
perforations. They are relative increase and seem related to NSAIDs. Better
management of this disease requires awareness of the population to self-medication.