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Ma, J.H., Shen, S.H., Zhang, G.W., Zhao, D.S., Xu, C., Pan, C.M., et al. (2010) Identification of a Locus for Autosomal Dominant High Myopia on Chromosome 5p13.3-p15.1 in a Chinese Family. Molecular Vision, 16, 2043-2054.

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• TITLE: Heredo-Familial Expression of Ametropia among Siblings of a Nigerian Family

  AUTHORS: Emmanuel Olu Megbelayin, Sylvia Iquo-Abasi Akpan

  KEYWORDS: Heredofamilial, Siblings, Ametropia

  JOURNAL NAME: Open Journal of Genetics, Vol.6 No.4, October 31, 2016

  ABSTRACT: A case series of 4 siblings who had auto-refraction and subjective refraction, refinement was with 0.25 Jackson Cross Cylinder. Presenting complaint was either blurring of distant vision or missing eye glasses. The eldest sibling started using eye glasses at 15 years of age while the other siblings commenced much earlier. Presenting visual acuities in 7 eyes ranged from 6/9 to 6/18, one eye of the eldest sibling had visual acuity of 6/36. Spherical errors had gender bias with the males more likely to be hypermetropic and the females more likely to be myopic. However, cylinder powers and axes were closely related in all siblings. It was concluded that heredo-familial traits could partly account for some of the striking similarities noted in the outcomes of refraction among the siblings.