TITLE:
Generation of Dose Volume Histograms Using Voxel Structure and the Monte Carlo Method in Low Dose Rate Brachytherapy
AUTHORS:
Artur F. Menezes, Hidmer Laulate, Juraci P. Reis Junior, Lucia H. Bardella, Alessandro Facure, Ademir X. Silva
KEYWORDS:
DVHs, Voxel, ICRP 110, MCNPX
JOURNAL NAME:
International Journal of Medical Physics, Clinical Engineering and Radiation Oncology,
Vol.5 No.4,
October
27,
2016
ABSTRACT: The Dose
Volume Histograms are tools commonly used in medical physics, for the analysis
of doses delivered to the tumors and organs at risk, during radiotherapy
treatments. However, there are few studies in the literature showing in details
the steps of its construction. This work presents the implementation and
evaluation of a computational methodology, for the construction of Dose Volume
histograms, generated from simulations using anthropomorphic and voxel
phantoms, in conjunction with the Monte Carlo code MCNP. The methodology was
evaluated considering brachytherapy planning of low dose rate, using 108 seeds
of I-125 with individual activities of 0.33 mCi performed on the simulator in
voxel recommended by ICRP 110. The dosimetric analysis after implantation
showed that the prostate received doses ranging from 0 to 360 Gy. We found the
values of 50, 145 and 160 Gy for the parameters D100,
D90 and D80 and 28%, 90%, 92% and
95% for the parameters V200,
V100, V90 and
V80. The rectum and bladder received maximum doses equal
to 41 and 60 Gy and found the values of 39 and 22 Gy and 58 and 42 Gy to the
parameters D0.1cc and D2cc,
respectively. The results after dosimetric implant proved satisfactory, which
validate the methodology described above.