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de Souza, C.R., de Oliveira, K.S., Ferraz, J.J., Leal, M.F., Calcagno, D.Q., Seabra, A.D., Khayat, A.S., Montenegro, R.C., Alves, A.P., Assumpcao, P.P., Smith, M. and Burbano, R.R. (2014) Occurrence of Helicobacter pylori and Epstein-Barr Virus Infection in Endoscopic and Gastric Cancer Patients from Northern Brazil. BMC Gastroenterology, 14, 179.
http://dx.doi.org/10.1186/1471-230X-14-179
has been cited by the following article:
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TITLE:
Synthesis and Anti-Cancer Activities of Resveratrol Derivatives
AUTHORS:
Xing Zheng, Liuying Yu, Xu Yao, Bo Lv, Zehua Yang, Qutong Zheng, Haiying Duan, Chen Song, Hailong Xie
KEYWORDS:
Resveratrol Derivatives, Wittig-Horner Reaction, MTT Method, Breast Carcinoma, Gastric Carcinoma
JOURNAL NAME:
Open Journal of Medicinal Chemistry,
Vol.6 No.3,
September
30,
2016
ABSTRACT: A novel series of resveratrol derivatives were synthesized according to Wittig-Horner reaction with 3,5-dihydroxybenzyl alcohol or 3,5-dimethoxybenzyl alcohol or 4-hydroxybenzyl alcohol as raw material and the inhibitory activities on breast carcinoma (MDA-MB-231) and gastric carcinoma cell lines (SGC-7901) in vitro were evaluated by the standard methyl thiazole tetrazolium (MTT) method. The result of biological test shows that some of resveratrol derivatives possess stronger anti-cancer activities than 5-FU. Compound 5c shows the strongest activity against breast carcinoma (MDA-MB-231) and gastric carcinoma cell lines (SGC-7901) with IC50 value of 50.19 ± 1.02 μM, 122.68.27 ± 2.04 μM, compared to that IC50 value of 5-FU is 98.59±3.61 μM,156.74±6.16 μM, respectively.