TITLE:
Development of Polycaprolactone/Poly(Vinyl Alcohol)/Clay Microparticles by Spray Drying
AUTHORS:
Mariana Sato de S. de B. Monteiro, Claudia Lopes Rodrigues, Eduardo Miguez, Maria Inês B. Tavares
KEYWORDS:
Microparticles, Spray Drying, Polycaprolactone, Poly(Vinyl Alcohol), Sodium Clay NT-25
JOURNAL NAME:
Materials Sciences and Applications,
Vol.7 No.10,
September
30,
2016
ABSTRACT: In this
study, nanostructured microparticles was developed with polycaprolactone (PCL),
poly(vinyl alcohol) (PVAL) and nanoparticles of the commercial sodium clay
NT-25® by using the spray drying technique. The systems
obtained were characterized by Nuclear Magnetic Resonance (NMR), Scanning
Electron Microscopy (SEM), Fourier Transform
Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Dynamic Laser Light
Scattering (DLS) and Differential Scanning Calorimetry (DSC). The NMR 13C
and FTIR techniques showed that both polymers were present in the
microparticles and the DSC analysis revealed a small variation in the glass
transition temperature of the PCL. The XRD and SEM analyses showed that the
microparticles produced were amorphous and had a concave morphology. The NT-25
nanoload reduced the microparticles’ size due to the multiple interactions
formed in the hybrid nanocomposite material. Therefore, it was possible to
develop microparticles by using
biodegradable and biocompatible polymers, with different polarities, allowing
the incorporation of hydrophilic and hydrophobic materials and enabling the
inclusion of otherwise incompatible materials in the same system.