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Doitsh, G., Galloway, N.L.K., Geng, X., Yang, Z.Y., Monrole, K.M., Zepeda, O., Hunt, P.W., Hatano, H., Sowinski, S., Isa, M.-A. and Green, W.C. (2014) Cell Death by Pyroptosis Drives CD4 T-Cell Depletion in HIV-1 Infection. Nature, 505, 509-514.

has been cited by the following article:

• TITLE: Estimation and Assessment of Plasma D-Dimer Levels in HIV Patients

  AUTHORS: Wafa Hamid Haroun Himmat, Nasr Eldeen Ali Mohammed Gaufri

  KEYWORDS: HIV, AIDS, D-Dimer, Sudan

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.4 No.10, September 30, 2016

  ABSTRACT: Background: The elevation of plasma D-dimer levels is fully described and associated with the increase of the mortality of patients with HIV. The present study was aimed to estimate and assess the plasma D-dimer levels in HIV patient. Material and Methods: A case control study done in May 2015. A total of 100 subjects were enrolled in this study; 50 were patients professionally diagnosed by HIV; 25 (50%) were males and 25 (50%) were females; their mean age is 35 years. Further 50 normal healthy individuals as normal control group: their gender and age were matched with patient groups. The platelets poor plasma (PPP) was immediately prepared from citrated blood, then the plasma D-dimer level was measured using (MISPA-i2 Reagent) Switzerland. Data were analyzed using statistical packing for social sciences program (SPSS) 20. Results: The D-dimer levels was significantly higher in patient with HIV compared with the normal healthy control group (Mean and STD 502.2 ± 287.8 vs 251.8 ± 152.7 P. value 0.01). Conclusion: The D-dimer level was significantly higher in patient with HIV compared with those in normal healthy control group.