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Beasley, C.M.Jr., Tollefson, G., Tran, P., Satterlee, W., Sanger, T. and Hamilton S. (1996) Olanzapine versus placebo and haloperidol: Acute phase results of the North American double-blind olanzapine trial. Neuropsychopharmacology, 14, 111-123. doi:10.1016/0893-133X(95)00069-P

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• TITLE: Withdrawal seizure associated with high dosage of aripiprazole and fluoxetine: a case report

  AUTHORS: Jian-An Su, Shih-Yong Chou, Ching-Shu Tsai, Tai-Hsin Hung

  KEYWORDS: Aripiprazole; High Dosage; Withdrawal Seizure

  JOURNAL NAME: Open Journal of Psychiatry, Vol.1 No.2, July 12, 2011

  ABSTRACT: Aripiprazole, a third-generation antipsychotic, has been considered to have a high safety profile and rare withdrawal symptoms. We reported the case of a schizophrenic patient with a significant obsession, who was treated with a high dosage of aripiprazole and fluoxetine. Generalized tonic-clonic seizure occurred two days after abruptly stopping these two medications. Gradually tapering aripiprazole is suggested in clinical practice, especially when using a high dosage.