TITLE:
A Case of Acute Renal Failure Associated with IgG4-Related Disease Presenting Both Tubulointerstitial Nephritis and Retroperitoneal Fibrosis
AUTHORS:
Hirohito Sugawara, Hideki Takizawa, Norihito Moniwa, Naoki Takamatsu, Yusuke Ohashi, Yayoi Ogawa
KEYWORDS:
IgG4 Related Disease, IgG4 Related Tubulointerstitial Nephritis, Retroperitoneal Fibrosis, Acute Renal Failure
JOURNAL NAME:
Open Journal of Nephrology,
Vol.6 No.3,
September
28,
2016
ABSTRACT: We report a case of IgG4-related disease presenting both tubulointerstitial nephritis and retroperitoneal fibrosis causing acute renal failure in a 63-year-old male. He was admitted to our hospital because of acute renal failure requiring emergent hemodialysis. Computed tomography showed a soft-tissue density mass with an irregular border in the retroperitoneum. The mass involved bilateral ureters and had caused acute renal failure by bilateral hydronephrosis. Because of a history of uveitis and high IgG4 levels, we considered a diagnosis of retroperitoneal fibrosis, IgG4-related disease. Kidney biopsy revealed IgG4-related kidney disease with interstitial nephritis. After relief of urinary obstruction by inserting ureteral catheters into the bilateral ureters, renal function recovered.