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Uehara, H., Miyamoto, M., Kato, K., Ebihara, Y., Kaneko, H., Hashimoto, H., Murakami, Y., Hase, R., Takahashi, R., Mega, S., Shichinohe, T., Kawarady, Y., Itoh, T., Okushiba, S., Kondo, S. and Katoh, H. (2004) Expression of Pigment Epithelium-Derived Factor Decreases Liver Metastasis and Correlates with Favorable Prognosis for Patients with Ductal Pancreatic Adenocarcinoma. Cancer Research, 64, 3533-3537.
http://dx.doi.org/10.1158/0008-5472.CAN-03-3725
has been cited by the following article:
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TITLE:
Prognostic Significance of Pigment Epithelium-Derived Factor Expression in Patients with Non-Small-Cell-Lung Cancer
AUTHORS:
Alexander Emmert, Angelika Oellerich, Laszlo Füzesi, Regina Waldmann-Beushausen, Friedrich A. Schöndube, Hanibal Bohnenberger, Bernhard C. Danner
KEYWORDS:
NSCLC, PEDF, Neoangiogenesis
JOURNAL NAME:
Advances in Lung Cancer,
Vol.5 No.3,
September
22,
2016
ABSTRACT: The
aims of this study were to examine prognostic significance of pigment epithelium-derived
factor (PEDF) in patients with stage IA-IIIB non-small cell lung cancer (NSCLC).
Using immunohistochemistry and multivariate analysis, we set out to investigate whether PEDF expression
could provide prognostic information in NSCLC in a cohort of 69 patients who
had undergone radical resection for NSCLC. The correlation between PEDF and the
clinical pathological features of stage I-III NSCLC after radical surgery were
analyzed as well as
influence on long term survival. No correlation between PEDF intensity, PEDF
area or PEDF area index and clinic opathologic
parameters was seen. PEDF values showed a slight correlation to the tumor
stage. There was a significant negative correlation (T = -0.288, p = 0.002)
between pathologic T-stage and median PEDF area and vice versa a positive
correlation (T = 0.227, p = 0.016) with median PEDF intensity. We could not
detect any correlation between PEDF and long term survival. For PEDF analysis, there was only a slight correlation between expression
and T-stage of the tumor.