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Mahomed, N.N., Barrett, J.A., Katz, J.N., Phillips, C.B., Losina, E., Lew, R.A., Guadagnoli, E., Harris, W.H., Poss, R. and Baron, J.A. (2003) Rates and Outcomes of Primary and Revision Total Hip Replacement in the United States Medicare Population. Journal of Bone and Joint Surgery, 85, 27-32.

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• TITLE: Antibiotic Bone Cement and Ultraviolet Light Use in Total Knee Arthroplasty

  AUTHORS: John B. Meding, Kenneth E. Davis, Merrill A. Ritter

  KEYWORDS: Antibiotic Bone Cement, Ultraviolet Light, Total Knee Arthroplasty, Infection, Complications

  JOURNAL NAME: Open Journal of Orthopedics, Vol.6 No.9, September 20, 2016

  ABSTRACT: Objective: The purpose of this study was to determine usefulness of antibiotic bone cement and UV light in primary Total Knee Arthroplasty (TKA). Patients and Methods: Between 1986 and 2008, 3105 TKAs were performed using 750 mg of cefuroxime per bag of cement (Group 1), 7537 using cefuroxime and UV light (Group 2), and 4573 using UV light and gentamicin premixed (Group 3). Results: The primary infection rate was 0.57% (87 acute postoperative infections). Of these, 27 (0.9%) were in Group 1, 44 (0.6%) were in Group 2, and 16 (0.35%) were in Group 3 (p = 0.0013). Kaplan-Meier survival in Groups 1 - 3 for reoperation for aseptic loosening of any component at 5 years was 0.9908, 0.9927, and 0.9959, respectively (p = 0.1315). Conclusion: Despite potential concerns mentioned in the literature, these results continue to support the use of antibiotic bone cement and UV lights during TKA.