TITLE:
SilTech: A New Approach to Treat Aerobic Vaginitis
AUTHORS:
Filippo Murina, Franco Vicariotto, Stefania Di Francesco
KEYWORDS:
Aerobic Vaginitis, Wet Mount Microscopy, Silver, Vaginal Soft Gel Capsule, Vaginal Inflammation, Leucorrhea
JOURNAL NAME:
Advances in Infectious Diseases,
Vol.6 No.3,
August
29,
2016
ABSTRACT: Background: The aerobic
vaginitis (AV) is characterized by increased levels of aerobic bacteria,
vaginal inflammation and depressed levels of lactobacilli. Objective: The
purpose of this study was to investigate the therapeutic efficacy of SilTechTMvaginal softgel capsules, containing
new microcrystals of silver monovalent ions, for aerobic vaginitis (AV).
Methods: This prospective study enrolled 32 women diagnosed with AV. All
recruited women were treated with SilTechTMvaginal softgel capsules once daily
for 7 days (one course). Therapeutic efficacy was evaluated based on clinical
and microscopic criteria, and cure rates were calculated. Women who were
improved (but not cured) received a second course of therapy. Patients
classified with clinical and microscopic failure were treated using other
strategies. Results: After one course of therapy, 59.2% (19/32) of women were
cured, 19.0% (6/32) were improved (but not cured) and 21.8% (7/32) failed to
respond to the therapy. After two courses of therapy, clinical improvement was
achieved in additional two women. The therapy was very well tolerated, and
during the entire study no drop out related to the SylTechTMvaginal capsules treatment was
observed; only two patients (6.2%) experienced a mild transient burning after
application. Conclusion: SylTechTMvaginal
capsules is an effective therapeutic option for patients with AV, and most
women with AV were cured with one course of therapy.