TITLE:
Comparison of the Skin Lipid Layer in Acne Vulgaris Patients after Treatment with 50% Lactobionic Acid, Corundum Microdermabrasion and a Combination of Both Means
AUTHORS:
Beata Marczyk, Paulina Mucha, Helena Rotsztejn, Elzbieta Budzisz
KEYWORDS:
Lactobionic Acid, Corundum Microdermabrasion, A Combined Method, Sebumeter, Acne Vulgaris, Facial Seborrhoea
JOURNAL NAME:
Journal of Cosmetics, Dermatological Sciences and Applications,
Vol.6 No.4,
August
18,
2016
ABSTRACT: Background: The uses of lactobionic acid, corundum microdermabrasion, and
a combined technique, are treatments supporting therapies for acne vulgaris and
seborrhoea. Objectives: The work was conducted to determine the effects of the
peeling with lactobionic acid, corundum microdermabrasion, and a combined
technique of both means on sebum secretion in acne vulgaris patients. Methods:
The peeling with 50% lactobionic acid, the corundum microdermabrasion, and the
combined technique were applied to 45 female patients divided into three groups
of fifteen people each. Every one treatment was given five times in two week
intervals. The measurements of sebum secretion were done within the T- and
U-zones using Sebumeter SM15 (Courage & Khazaka, Germany). The last (sixth)
measurement was performed two weeks after the last treatment. Results: Decrease
in the level of sebum secretion was found during second or third measurement.
Two weeks after the last treatment, the biggest decrease in the level of sebum
secretion was observed in the patients treated with lactobionic acid, followed
by those treated with the combined method. Conclusions: Treatments consisting
of the peeling with lactobionic acid, corundum microdermabrasion, or the
combined technique, brought significant decrease in the level of sebum
secretion. The biggest decrease was observed in the patients treated with
lactobionic acid, which being structurally similar to α-hydroxyacids exerts exfoliating properties. The combined method
was also effective, because of increased skin penetration of the active
ingredients, resulting from the abrasion of stratum corneum during the corundum
microdermabrasion. The corundum microdermabrasion alone was the least effective
approach.