TITLE:
A Case of Megaloblastic Anemia with Thrombocytopenia
AUTHORS:
Somayeh Moghadam, Maryam Ghorbani
KEYWORDS:
Megaloblastic Anemia, Folic Acid, Vitamin B12
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.6 No.9,
August
8,
2016
ABSTRACT: Megaloblastic anemias are a group of hematologic disorders in which
abnormal DNA synthesis causes blood and bone marrow disorders. This type of
anemias occurs as a result of folic acid deficiency or impaired vitamin B12 absorption.
The prevalence of this type of anemia is highly variable worldwide and
megaloblastic anemia caused by lack of vitamin B12 (cyanocobalamin) is rare
during pregnancy [1]. In this case report, we report follow-ups conducted for a
pregnant 33-year-old woman, G2, P1, with a history of previous natural
childbirth who attended Kamali Hospital due to labor pain associated with
severe thrombocytopenia. Although this woman was injected 10 units of PLT and
also vitamin B12 (cyanocobalamin), folic acid and corticosteroids in the course
of treatment, her platelet level has not yet returned to normal levels after 6
months and she is still being treated.