TITLE:
Assessment of Acute Episodes in Chronic Stable Angina: A Clinical-Laboratory Approach to the Use of the Coronary Vasodilator Propatyl Nitrate
AUTHORS:
Gerson Goldwasser, Renato Kaufman, Carlos Pereira Nunes, Alexandre Hid, Stephanie Wrobel Goldberg, Alessandra Santos, Lisa Oliveira, Adenilson de Souza da Fonseca, Mauro Geller
KEYWORDS:
Propatyl Nitrate, Stable Chronic Angina Pectoris, Seattle Angina Questionnaire
JOURNAL NAME:
World Journal of Cardiovascular Diseases,
Vol.6 No.7,
July
26,
2016
ABSTRACT: Background/Objectives: Propatyl nitrate is a coronary vasodilator with immediate and prolonged action, indicated in the treatment and prevention of acute angina pectoris episodes. Methods: This was an open, self-paired comparative study performed at UNIFESO Medical School evaluating the clinical and laboratory results of treatment with propatyl nitrate in patients with chronic stable angina pectoris. Subjects received 10 mg of propatyl nitrate, at the dose of three sublingual tablets per day, to be taken at 8:00 A.M., 2:00 P.M., and 8:00 P.M. Subjects returned to the study center after 15 days of treatment for Visit 2 assessments, and at the end of the 30-day treatment period (Visit 3). Results: A total of 200 subjects were included in the study. There was a statistically significant reduction in blood pressure (p