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Yamada, T., Tashiro, K., Moriwaka, F., Fujiki, N., Ito, K., Honma, S., et al. (1989) Two Cases of Familial Spastic Paraparesis with Amyotrophy of the Hands. No To Shinkei, 41, 583-588.

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• TITLE: Severe Generalized Spinal Cord Atrophy and Marfan Syndrome: A Case Report

  AUTHORS: Huanquan Liao, Hongyan Zhou, Ling Chen

  KEYWORDS: Generalized Spinal Cord Atrophy, Marfan Syndrome

  JOURNAL NAME: Open Access Library Journal, Vol.2 No.11, November 12, 2015

  ABSTRACT: Generalized spinal cord atrophy is rare. Several causes can be found responsible for this entity. Marfan syndrome (MS) is a clinically and allelically heterogeneous, heritable connective tissue disorder. Previous study has implicated neuromuscular involvement in this syndrome. Here, we report the description of a patient with generalized spinal cord atrophy, which may be attributed to MS. Though not all patients represent with spinal cord atrophy, our case suggests that generalized spinal cord atrophy may occur in a subgroup of MS patients. Our finding underscores the need to inform medical practitioners that neurologic involvement, especially generalized spinal cord atrophy, can occur in patients with MS. Further studies are warranted in order to better clarify this causal relationship association between MS and spinal cord atrophy.