TITLE:
The Comparison of Clinical and Biochemical Outcomes in Off-Pump and Conventional Coronary Artery Bypass Grafting Surgery
AUTHORS:
Z. Temizturk, D. Azboy, K. Karapınar, I. Ince, M. Bozguney, S. Sahinalp, O. Ersoy, A. Bulut, E. Yucel
KEYWORDS:
Coronary Artery Bypass Grafting, On-Pump, Off-Pump, Left Ventricular Functions
JOURNAL NAME:
Open Access Library Journal,
Vol.2 No.8,
August
18,
2015
ABSTRACT: Objective: There is no common concencus the clinical
results of coronary artery bypass grafting (CABG) surgery patients who
underwent off-pump or conventional techniques. Our aim of this study was to compare
the changes of myocardial functions, patients’ clinical results, biochemical
marker release during surgery and postoperatively in On- and Off-Pump CABG
surgery. Method: A consecutive series of 50 coronary artery disease (CAD)
patients who underwent elective CABG surgery included for this study. The
patients were divided into two groups (Group 1, N = 25 and group 2, N = 25).
Demographic data including the patients’ age, gender, body mass index (BMI),
diseased coronary artery numbers, LVEF were similar. Postoperative red package blood cell, fresh frozen
plasma, and thrombocyte requirements were high in On-Pump group (p p p > 0.05). However, cTnI levels were
significantly higher in the on-pump group (p = 0.0001). Postoperative LVEF decreased significantly in both groups when
compared to preoperative echocardiography examinations (p = 0.001). But the changes of postoperative LVEFs in both groups were not statistical significant (p > 0.05). Conclusion: Our study results indicated that cardiac
enzyme release was high after On-Pump CABG surgery. However, LVEF decreased in both techniques. There were some advantages of
OPCAB operations such as decrease of inflammatory responses and angina pectoris
incidence due to extracorporeal circulation; however, these techniques did not
affect postoperative mortality and morbidity. Therefore, in selected cases to
provide longer operation time, Off-Pump CABG could be used but it has no
superiority over On-Pump CABG surgery.