TITLE:
Prevalence of Obstructive Sleep Apnoea in Patients with Idiopathic Pulmonary Fibrosis
AUTHORS:
Gabriela C. Tabaj, Daniela Visentini, Patricia Malamud, Cecilia González Ginestet, Glenda Ernst, Gabriela Rando, Mariana Salomon, Georgina Gramblicka
KEYWORDS:
Idiopathic Pulmonary Fibrosis, Obstructive Sleep Apnea, Polisomnography, Prevalence
JOURNAL NAME:
Open Access Library Journal,
Vol.2 No.6,
June
25,
2015
ABSTRACT: Background: Over the last years,
increasing attention has been focused on the prevalence of obstructive sleep
apnea (OSA) in idiopathic pulmonary fibrosis (IPF). Objective: To determine the
prevalence of OSA in a group of patients diagnosed with IPF. Materials and
Methods: Analytic retrospective study. Data were collected from the medical
records of all patients diagnosed with IPF who had polysomnography requested as
part of the study protocol in patients with interstitial lung diseases (ILD).
Results: 36 patients were studied, 26 of who were male. The mean age was 67.55
± 6.39 years old. Mean forced vital capacity (FVC) was 2.12 ± 0.76 liters. The
mean body mass index (BMI) was 28.78 ± 4.24. The Epworth Sleepiness Scale (ESS)
average was 7.55 ± 5.01 and the mean apnea hypopnea index (AHI) was 12.69 ±
19.40. Of all the patients studied, 17 (47.22%) had OSA with an AHI ≥ 5. Of these, 9 (25%) had AHI ≥ 10. In the
group of patients with OSA (n = 17), 9 (52.94%) had mild OSA (AHI between 5 and
15) and 8 (47.05%) moderate to severe OSA (AHI ≥ 15). Conclusions: In our
series of 36 patients with IPF we found a prevalence of OSA of 47.22%. We found
no correlation between ESS and the BMI with the presence of OSA in these patients,
suggesting that these
assessments may be less than optimal screening tools for OSA in
IPF.