TITLE:
A Rare Case of Chronic Recurrent Multifocal Osteomyelitis with Undifferentiated Juvenile Idiopathic Arthritis, Uveitis, and Psoriasis
AUTHORS:
Yongdong Zhao, Shannon K. Foster, Todd J. Murdock, Margret Schlesinger, Carol A. Wallace
KEYWORDS:
Juvenile Idiopathic Arthritis, Uveitis, Psoriasis, Chronic Recurrent Multifocal Osteomyelitis, Infliximab, Ustekinumab
JOURNAL NAME:
Case Reports in Clinical Medicine,
Vol.5 No.7,
July
14,
2016
ABSTRACT: We report here a 17-year-old boy with a complicated presentation of undifferentiated juvenile idiopathic arthritis, vision-threatening uveitis and chronic recurrent multifocal osteomyelitis (CRMO) in the pelvis. His severe iritis needed subtenon injections and only responded to infliximab after failing multiple biologics. Unfortunately he later developed infliximab-associated psoriasis. A combination of infliximab and ustekinumab induced remission of his arthritis, osteomyelitis, uveitis and psoriasis without experiencing severe infections.