TITLE:
MPV Values in Children with Adenoid Hy-pertrophy and Correlation with Adenoid Size
AUTHORS:
Esra Akyüz Özkan
KEYWORDS:
Adenoid Size, Adenoid Vegetation, Children, Mean Platelet Volume
JOURNAL NAME:
Open Access Library Journal,
Vol.3 No.1,
January
15,
2016
ABSTRACT: Background: Adenoid hypertrophy (AH) leads to chronic upper airway
obstruction. Upper airway obstruction may cause pulmonary hypertension and
right ventricle dysfunction. Mean platelet volume (MPV) may be used as a marker
of platelet activation and it is shown that MPV is related to cardiovascular disorders.
We investigated in our study if MPV is correlated with adenoid size and can be
used as an indicator of obstruction due to adenoid hypertrophy. Methods: 95
children with AH and 99 healthy controls were enrolled in the study. White
blood cell, hemoglobin, platelet, Mean platelet volume (MPV) levels were
measured before adenoidectomy. Lateral cephalometric graphs were obtained from
all patients to measure adenoid/nasopharynx ratio (A/N). The distance between
the outermost point of convexity of adenoid shadow and basiocciput was divided to the distance between sphenobasiocciput and posterior end
of the hard palate. A/N ratio and MPV levels have been correlated by using
Pearson correlation test. Results: There were 45 male and 50 female patients
between the ages of 2 and 14 years (mean age: 6.47 ± 2.44). There were no significant
differences between children with AH and controls regarding white blood cell, hemoglobin,
platelet, MPV and A/N ratio. We didn’t detect any correlation between MPV
levels and A/N ratio. Conclusion: MPV level was in normal limits in AH children
and there was no significant relation between MPV and adenoid severity.