TITLE:
Activities of Lactate Dehydrogenase, Methemoglobin, Carboxyhemoglobin and Sulfhemoglobin Concentrations in the Blood of Albino Rats Exposed to Cashew Seed Fume
AUTHORS:
Makinwa Tunmise Tope, Ibiyemi David Adedotun, Alabi Toyin Dorcas, Okunade Muda Bode, Oniwon Wisdom Otaru, Adeusi Tomilola Esther
KEYWORDS:
Cashew Seed Fume, Methemoglobin, Sulfhemoglobin, Carboxyhemoglobin, Albino Wistar Rats
JOURNAL NAME:
Open Access Library Journal,
Vol.3 No.1,
January
14,
2016
ABSTRACT: Smoke produced in cashew processing factories during roasting of the seed
contains toxic chemicals which have adverse health effects on workers exposed
to it. This study investigated the effect of cashew seed fume on lactate
dehydrogenase (LDH) activity, methemoglobin (Hi), carboxyhemoglobin (HbCO) and sulfhemoglobin (SHb) in the blood of rats exposed to cashew seed fumes (CSF), via the dynamic
exposure system. Eighteen (18) male albino rats were used; they were divided into
three groups of six animals each as: control, rats exposed for two (2) hours
and rats exposed four (4) hours for five days. The results showed that serum level
of LDH in rats exposed to CSF was significantly (P P P > 0.05) differences in the % methemoglobin level of rats in
all groups. This study revealed that exposure to CSF may have adverse effects
on the lungs and may also result in system poisoning. This should be a cause of
concern for industrial regulatory bodies who should regulate the safety of cashew
factory workers.