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Takashima, S., Koyama, H., Kasumi, F., Kimijima, I., Ohkawa, T., Takatsuka, Y., Okumura, K., Kodama, H., Nishi, T., Sano, M., Fukutomi, T. and Kobayashi, S. (1995) Evaluation of the Quality of Life in Breast Cancer Patients Treated with Breast-Conserving Therapy. Journal of Japan Society for Cancer Therapy, 30, 1641-1652. (In Japanese with English Abstract)

has been cited by the following article:

• TITLE: Quantitative Assessment of Chronic Skin Reactions Including Erythema and Pigmentation after Breast Conserving Therapy

  AUTHORS: Miho Kawashima, Miwako Nozaki, Kazuhiro Komazaki, Ryuko Yamamuro, Kazuo Ishizuna, Makoto Kojima

  KEYWORDS: Breast Cancer, Erythema Index, Melanin Index, Breast-Conserving Therapy

  JOURNAL NAME: Advances in Breast Cancer Research, Vol.5 No.3, July 8, 2016

  ABSTRACT: Purpose: To evaluate long-term skin reactions following breast-conserving therapy by using the melanin-erythema index meter. Patients and Methods: 164 patients were followed for at least three years after breast-conserving therapy. For both the erythema and the melanin indices, the ratio of the irradiated-side index to the non-irradiated-side index was calculated. The time course of index ratios alternation was examined. Influences from additional therapies and patients’ age were also evaluated. Result: Both erythema and melanin index ratios of the breast skin were recovered to pre-radiation level three years after radiotherapy. However, both index ratios of the area administrated with 10-Gy boost irradiation were still high even after five years after radiotherapy. Endocrine therapy, chemotherapy and age had no significant influence on skin color reactions three years after radiotherapy. Conclusion: Quantitative assessment using the melanin-erythema index meter demonstrated that chronic skin reactions following breast conserving therapy had recovered to pre-radiation level for three years after irradiation except for the 10-Gy boost irradiated area.