TITLE:
Assessment of Antiretroviral Efficacy of the Medicinal Synthetic Aluminum-Magnesium Silicate {Al4(SiO4)3 + 3Mg2SiO4 → 2Al2Mg3(SiO4)3}
AUTHORS:
Maduike C. O. Ezeibe, Dahiru Aleeyu, Nnaemeka K. Aneke, Thompson N. Obarezi, Ijeoma J. Ogbonna, Ekenma Kalu
KEYWORDS:
HIV, MSAMS-Nanoparticles, Opposite Electrical Charges, HIV-Positive, Lymphopenia, HIV-Antigens/Antibody Negative, Lymphocytosis
JOURNAL NAME:
World Journal of AIDS,
Vol.6 No.2,
June
29,
2016
ABSTRACT: HIV/AIDS patients were treated, daily, with
MSAMS (50 mg/kg), MSAMS-stabilized Ampicillin trihydrate (7.5 mg/kg) and
immunace extra-protectionM? (1 tablet), for one month and then, with only MSAMS
and the immune stimulants. They were tested, monthly, for viral loads and CD4-
lymphocytes counts. Those whose viral loads became undetectable were tested for
HIV confirmation (antigens/antibody). Their mean-viral load increased (P =
0.020) from 1820.30 ± 868.75 to 2855.90 ± 960.98 after first month, before reducing
(P = 0.0.030) to: 1565.20 ± 743.17; 759.20 ± 473.65; 345.50 ± 115.01; 192.80 ±
97.40; 95.00 ± 55.80; 37.40 ± 26.46; 17.50 ± 16.88 (undetectable). Their
mean-CD4 count was 496.80 ± 194.39 (lymphopenia). It reduced (P = 0.008) to
263.90 ± 149.26 after first month, before increasing (P = 0.001) to: 507.90 ±
133.19; 692.70 ± 113.34; 840.20 ± 139.41; 1007.30 ± 163.50; 1537.10 ± 302.10;
1924.60 ± 247.45; 2707.00 ± 837.87 (lymphocytosis). Patients whose viral loads
became undetectable tested HIV-negative, one month after. CD4-lymphocytes
count, approximating to zero-viral load, calculated from equation (Y = 2297.80 － 1.4731X) of line of best fit of graph of their viral loads onCD4-lymphocytes
counts, was 1559.84/ml.