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Rodrigues, R.M., Gon?alves, C., Souto, R., Feres-Filho, E.J., Uzeda, M., and Colombo, A.P. (2004) Antibiotic re-sistance profile of the subgingival microbiota following systemic or local tetracycline therapy. J Clin Periodontol, 31, 420-427.

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• TITLE: New insights in understanding dental caries and periodontal disease: the avalanche model

  AUTHORS: Peter Gaengler, Ljubisa Markovic, Dagmar Norden, Rainer A. Jordan

  KEYWORDS: Dentistry; Dental Caries; Etiology; Model; Pathology; Periodontal Disease

  JOURNAL NAME: Health, Vol.1 No.4, December 29, 2009

  ABSTRACT: Biology is based on evolution; therefore, eu-kariotes like plants, animals and human beings are living in harmony with their procariote an-cestors. If this is obviously the normal way of life, then pathobiology follows the same basic principles. The highly complex harmony of the living world may be disrupted, and a punctuated disease starts which is different from the health equilibrium. To reflect this biological archetype on the main diseases in dentistry - caries and periodontitis - the avalanche model is being proposed based on scientific and clinical evi-dence. This way of argumentation does influ-ence the strategic planning of preventive and curative programmes in dental research as well as in daily practise.