TITLE:
Antenatal Diagnosis of Isolated Total Arhinia in the Second Trimester of Pregnancy
AUTHORS:
D. Leroy, E. Slachmuylder, M. Popijn, M. Cassart, A. Massez, N. D'Haene, J. Désir, A. Vandermaelen, C. Daelemans, G. Ceysens, C. Donner
KEYWORDS:
Antenatal, Ultrasound, Arhinia, Diagnosis, Pregnancy
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.6 No.7,
June
16,
2016
ABSTRACT: Congenital arhinia is a very rare condition especially when it is
isolated. Most of arhinia are identified after birth and only five prenatal
cases are described in the literature. Generally, arhinia is associated with
other malformations mainly craniofacial anomalies. Genetics aberrations are uncommon.
Our case was diagnosed in the second trimester of pregnancy and we found no
associated anomaly except for a single umbilical artery. Autopsy confirmed the
diagnosis and neuropathology analysis revealed the absence of olfactory bulbs
and tracts.