TITLE:
Successful Surgical Treatment of Metachronous Oligometastases from Non-B, Non-C Hepatocellular Carcinoma
AUTHORS:
Haruchika Yamamoto, Yuji Hirami, Tomohiro Toji, Yoko Shinno, Tetsuya Ota, Minoru Naito, Akio Andou
KEYWORDS:
Hepatocellular Carcinoma, Mediastinal Metastases, Rib Metastases, Oligometastases
JOURNAL NAME:
Open Journal of Thoracic Surgery,
Vol.6 No.2,
May
31,
2016
ABSTRACT: Hepatocellular Carcinoma (HCC) rarely metastasizes to bone or mediastinum. In some patients, surgical treatment of oligometastatic lesions from colorectal cancer, breast cancer, or non-small cell lung cancer results in satisfactory survival. However, data concerning oligometastatic lesions from HCC are scarce. We report the case of a patient with long-term survival after resection of metachronous oligometastases of HCC. A 54-year-old woman underwent hepatic resection for non-B, non-C HCC. A solitary left tenth rib tumor was detected 20 months after initial surgery and was surgically resected. A solitary mediastinal tumor was detected 6 months after the second operation and the patient again underwent surgical resection. Histopathological examination of both lesions confirmed metastasis of HCC. The patient has had no further recurrence 7 years after initial surgery without chemotherapy or radiotherapy.