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Marbois, B., Xie, L.X., Choi, S., Hirano, K., Hyman, K. and Clarke, C.F. (2010) Para-Aminobenzoic Acid Is a Precursor in Coenzyme Q6 Biosynthesis in Saccharomyces cerevisiae. The Journal of Biological Chemistry, 285, 27827-27838.
http://dx.doi.org/10.1074/jbc.M110.151894

has been cited by the following article:

• TITLE: Reactions with Aminobenzoic Acids via Diazonium Salts Open New Routes to Bio-Derived Aromatics

  AUTHORS: Anthony Farlow, Jens Olaf Krömer

  KEYWORDS: Aminobenzoic Acid, Terephthalic Acid, Salycilic Acid, Sandmeyer Cyanations

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.6 No.2, May 27, 2016

  ABSTRACT: Aromatics have a broad application in our everyday life ranging from plastics, coatings and fibres, to food and pharmaceuticals. To date the bulk of these aromatics is derived from naphtha-based pet-rochemistry. However, recent progress in the fermentative production of metabolites using renew-able resources and engineered microbes has enabled the production of bio-precursors, such as 4-amino benzoic acid (pABA) and 2-amino benzoic acid (oABA). In this work we explored the feasibility of Sandmeyer reactions for the conversion of pABA to terephthalic and oABA salicylic acid, providing two very important platform chemicals for the chemical and pharmaceutical industries. We could demonstrate that both acids can be obtained from the amino benzoic acids derived from the shikimate pathway in microbes and plants. Good conversions could be achieved using Sandmeyer reactions at mild conditions with biodegradable reagents and without organic solvents.