Article citationsMore>>

Levin, D.E., Hollstein, M., Christman, M.F., Schwiers, E.A. and Ames, B.N. (1982) A New Salmonella Tester Strain (TA102) with A-T Base Pairs at the Site of Mutation Detects Oxidative Mutagens. Proceedings of the National Academy of Sciences of the United States of America, 79, 7445-7449. http://dx.doi.org/10.1073/pnas.79.23.7445

has been cited by the following article:

• TITLE: Antimutagenic and DNA Damage Protective Activities of a Grape Extract from Vitis vinifera

  AUTHORS: Zuzana Rybková, Kateřina Malachová, Jiří Červeň, Hana Sezimová, Petr Pečinka

  KEYWORDS: Ames Test, Antimutagenicity, Free Radical Scavenging, DNA Strand Scission, Vitis vinifera

  JOURNAL NAME: Journal of Biosciences and Medicines, Vol.4 No.6, May 24, 2016

  ABSTRACT: Antimutagenic and DNA protective effect of an extract VinOserae from Vitis vinifera grapes on oxidative DNA damage was investigated. The extract’s ability to inhibit mutagenicity induced by tert-butyl hydroperoxide (t-BHP) and hydrogen peroxide (H2O2) was determined with Ames test using Salmonella typhimurium His? TA102 strain. Inhibition values of 44.2% and 67.0% were detected for t-BHP and H2O2, respectively. A protective ability of the extract against DNA strand scission induced by hydroxyl radicals was studied with plasmid pBluescript II SK(-). The analysis of DNA strand breaks in plasmid DNA showed a significant inhibition of DNA damage.