TITLE:
Hemophagocytic Lymphohistiocytosis Caused by Pyogenic Liver Abscess during Pregnancy: A Case Report and Literature Review
AUTHORS:
Kanako Ota, Kazumi Kawahara, Harumichi Banno, Koji Nishijima, Yoshio Yoshida
KEYWORDS:
Hemophagocytic Lymphohistiocytosis, Pregnancy, SIRS, Sepsis, Pyogenic Liver Abscess
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.6 No.5,
April
26,
2016
ABSTRACT: Introduction: Hemophagocytic lymphohistiocytosis during pregnancy is a
rare and severe condition, and timely diagnosis is quite difficult. We present
the first case of hemophagocytic lymphohistiocytosis caused by pyogenic liver
abscess during pregnancy and discuss the clinical presentation. Case Presentation:
A 26-year-old Japanese primigravida at 23 weeks of gestation complained of
extremely high fever with a fast heart rate (140 beats per minute). She
presented with systemic inflammatory response syndrome (SIRS). Only 2 days
later, she died. Autopsy findings proved that this was the first case of
hemophagocytic lymphohistiocytosis caused by pyogenic liver abscess during
pregnancy. Conclusion: Hemophagocytic lymphohistiocytosis should be considered
when patients meet the SIRS criteria, especially whose clinical presentation
includes extremely high fever (39°C) and a fast heart rate (greater than 110
bpm) during pregnancy, despite relatively normal laboratory data, because such
vital signs may be associated with the onset of hemophagocytic
lymphohistiocytosis.